Here are some tips that makes troubleshooting easy:

1) Check the event log
2) Google it
3) Reboot
4) Run IISreset
5) Empty the Recycle Bin
6) Hit [CTRL]+[BREAK]
7) Kill the ASPNET worker process
8) Clear Temporary Internet Files
9) Touch the config file
10) Degauss the monitor (Not that applicable any more, I suppose)
11) Simmer ground rhino horn on a bed of whale pancreas
12) "get latest" and rebuild
13) Login as admin
14) Run ipconfig /renew (Windows)
15) Check if CAPSLOCK is on.
16) Run a virus scan
17) Download the latest CTP
18) Disable and then re-enable the network interface
19) Restart services (some/most/all)
20) Change your password
21) Unplug your router, and leave it unplugged for 10 seconds before plugging it back in
22) Clear your Cookies
23) Add current site to your "Trusted Zones"
24) Disable javascript
25) Try to ping the server
26) Press 'clean solution' from the context menu in the solution explorer
27) Repair the installation
28) Run large magnets over all hard drives
29) Check the network cable.
30) Check the network cable again.
31) Defrag the hard drive
32) Try it in a different browser
33) Run an Anti-Malware scan
34) Minimize all windows and check for a modal dialog
35) Ensure configuration is correct(seriously)
36) See what has changed recently
37) Run process monitor
38) Run chkdsk /v (Windows)
39) Revert all check-ins from anyone named 'Gazza'
40) Run the windows update service(God help us all)
41) Remove and then recreate all Bluetooth partnerships
42) Do a hardware reset on your mobile device
43) Decompile + Monkey Punch + Duck Slap + Donkey Whack
44) What would jesus do?
45) Look for suitable workarounds
46) Re-calibrate your Geiger counter
47) Check for packet storms
48) Best to rule out toxicological contamination early on
49) Describe the problem in terms even a child can understand
50) Apply duct tape
51) Increase the timeout duration
52) Increase the maximum threadpool size
53) Write to your local minister or government representative
54) Try using the Microsoft Online Crash Analysis to submit your crash dump bucket-id
55) Disable the customer experience improvement program
56) Eat liver of sacred monkey
57) Import the decryption certificate to the local client certificate store
58) Ensure SQL server is setup for mixed mode authentication
59) Bypass proxy server for local addresses
60) Check the hosts file and the routing tables
61) Use filemon to locate any other log files being accessed
62) Check the BIOS
63) Update the device drivers for all peripherals
64) Attach a debugger, get a memory dump, look at it in a hex reader and post it to a forum
65) Cleanse all user inputs
66) Put a try catch around it
67) Replace the batteries in your wireless mouse and keyboard
68) Recompile all DLL's
69) Uninstall the old version, re- install the new version, apply hot fixes patches and upgrades
70) Remove the case from your computer, and aim a fan at it
71) Check that you haven't been blacklisted
72) Run diagnostic checks on surge protection units
73) Add an index
74) Remove an index
75) Recalculate indexes
76) Ensure FTP uses passive mode
78) Recalculate statistics
79) Reboot in safe mode
80) Check kerberos delegation
81) Review query plan
82) If 'automatically detect settings' is checked/unchecked, then uncheck/check it
83) Kill rogue processes in Task Manager
84) Run memtest.exe
85) Boot from your Emergency Repair Disks
86) Follow standard KNOPPIX data recovery procedures
87) Tweak-UI
88) Uninstall Adobe PDF Reader
89) Insert "Debug.WriteLine("up to line 53");" where appropriate
90) Set tracelevel to verbose
91) Flush buffers
92) % truss -t \!all -t open a.out
93) Use CDB or WINDBG. Add in SOS for CLR issues.
94) Field test any lightning protection devices
95) Use a temperature gauge on all hardware components, and compare against safe operating limits from 
96) Run it inside a VM
97) Check the DPI.
98) Search the knowledge base
99) Enable Javascript debugging
100) Turn off friendly HTTP error messages in IE
101) Set the current culture to en-US
102) Attach a multi-meter
103) Roll back to your most recent backup
104) Check for GC pressure
105) Empty the MSI cache
106) Temporarily allow popups
107) Look in your spam folder. Check it again. Now check it again. 
108) Recompile. Wait. Recompile.
109) Turn off Windows Firewall
110) Run CASPOL and give everything full trust
111) Put yourself in the shoes of the program itself. If you were the program, what would you do?
112) Ask Hanselman
113) Try WireShark. Failing that, try fiddler. What does tracert show?
114) Check the blueprints and read over the UML.
115) Implement the retry pattern.
116) RTFM
117) Delete the BIOS
118) Attach anti-static wrist strap on every appendage
119) Sit inside a Faraday cage
120) Insert "alert('here');" where appropriate
121) Overwrite every byte in memory the standard five times as pre-scribed by NSA guidelines
122) Reinstall the operating system from the original media provided by the supplier
123) Add a LOCK statement
124) Blame Irwin the intern
125) Blame the guy who left last week
126) Blame the ESL guy
127) Blame DNS
128) Add a sleep statement
129) Apply a fudge factor.
130) Run a spell checker over your code
131) Light some candles. Sacrifice chicken/goat.
132) Set all DWORD's to 0 in the registry. Then delete the registry
133) Drop all databases.
134) Unregister and re-register all DLLs
135) Reboot 3 times
136) Drink your own urine
137) Run prime95 overnight
138) Recompile the kernel
139) Do the packets hop subdomains, and if so does NAS require a NAS forwarding service -- how about VLAN?
140) Track down the original programmers who wrote the system, apply percussive trauma therapy.
141) Uninstall java
142) Underclock it
143) Ignore it
144) Post a request for comment on theDailyWTF
145) Ask for correlating evidence that the problem even exists
146) Sharpen your wooden stakes before proceeding any further
147) Melt silver crucifixes onto tips of all bullets
148) Fill your water bottle with holy water
149) Call tech support
150) Check when daylight savings begins
151) Remove everything from STARTUP folder
152) Plan and enact your fire evacuation plan
153) Bathe in holy water
154) Increase dosage on all medications. Check for interactions.
155) Bury heart of an Ox at midnight under crossroads on full moon
156) Clean up your desk
157) Check that pump's suction pipe is elevated above bottom of pond. (Float the inlet 30 to 40 
     centimetres below the water surface)
158) Wear shoes with six inch cork soles
159) Wear raincoat, goggles, breathing apparatus
160) Climb into an anti static bag
161) Always use a condom
162) Check pressure reading on gauges number 1 and 2
163) Run it through an Oscilloscope
164) Check your immunization schedule is up to date
165) Check for seismic/tectonic activity, solar flares, tsunami, meteor showers.
166) Go and get a coffee. come back and look at it with a fresh set of eyes.